Product Datasheet
ARID1A Antibody
Catalog Number: 49272
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:O14497
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- recombinant protein
- appl_detail:
IHC: 1:50-1:200
ICC: 1:50-1:200
- other_names:
- actin-dependent regulator of chromatin subfamily F member 1 antibody ARI1A_HUMAN antibody ARID domain containing protein 1A antibody ARID domain-containing protein 1A antibody ARID1A antibody AT rich interactive domain 1A (SWI lik
- Purification:
- ProA affinity purified
- Applications:
- ICC/IF, IHC
- Background:
- The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2α) and Brg-1 (also designated SNF2β) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits, such as BAF250a (p270 or ARID 1A) and BAF250b(ARID1B), are thought to play regulatory roles.
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