Product Datasheet
SOX1 Antibody
Catalog Number: 49247
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:O00570
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- recombinant protein
- appl_detail:
- WB: 1:500-1:1000
IHC: 1:50-1:100
ICC: 1:50-1:100
- other_names:
- Sex determining region Y box 1 antibody sox1 antibody SOX1_HUMAN antibody SRY antibody SRY box containing gene 1 antibody SRY related HMG box gene 1 antibody Transcription factor Sox-1 antibody
- Purification:
- ProA affinity purified
- Applications:
- WB, ICC/IF, IHC
- Background:
- Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.
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