Product Datasheet
14-3-3 alpha+beta Antibody
Catalog Number: 49215
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P31946
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- recombinant protein
- appl_detail:
- WB: 1:1,000-5,000
IHC: 1:50-1:200
ICC: 1:100-1:500
FC: 1:50-1:100
- other_names:
- 14 3 3 alpha antibody 14 3 3 protein beta/alpha antibody 14-3-3 protein beta/alpha antibody 1433B_HUMAN antibody Brain protein 14 3 3 beta isoform antibody GW128 antibody HS 1 antibody KCIP-1 antibody KCIP1 antibody
- Purification:
- ProA affinity purified
- Applications:
- WB, ICC, IHC, IP, FC
- Background:
- Members of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axonally transported to the nerve terminals. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of signal transduction pathways, including those involved in cell cycle regulation and cell survival. Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in signaling pathways mediated by serine/threonine protein kinases. Evidence indicates 14-3-3 is required for Raf 1 kinase activity and phosphorylation among many other functions.
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