Product Datasheet  
CDC42EP1 Antibody  
Catalog Number: 49211  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q00587
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • recombinant protein
  • reactivity:  
  • Hu
  • appl_detail:  
  • WB: 1:1,000-1:2,000



  • other_names:  
  • 55 kDa bone marrow stromal/endothelial cell protein antibody
    Binder of Rho GTPases 5 antibody
    Bone marrow stromal/endothelial cell protein, 55-KD antibody
    BORG 5 antibody
    BORG5 antibody
    BORG5_HUMAN antibody
    CDC42 effector pro
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB
  • Background:  
  • MSE55 also known as Borg5 or binder of Rho GTPases 5 is a Cdc42 effector protein that induces long cellular extensions in fibroblasts. MSE55 also increases and mediates actin cytoskeleton reorganization at the plasma membrane. MSE55 is a nonkinase CRIB (Cdc42/Rac interactive-binding) domain-containing molecule. An intact CRIB domain is required for the GTP-dependent binding of MSE55 to Cdc42. MSE55 is expressed in a tissue-specific manner in endothelial and bone marrow stromal cells. MSE55 may have a functional role in hematopoiesis or as a negative regulator of Rho GTPase signaling.



 
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