Product Datasheet
CDC42EP1 Antibody
Catalog Number: 49211
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q00587
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- recombinant protein
- appl_detail:
- WB: 1:1,000-1:2,000
- other_names:
- 55 kDa bone marrow stromal/endothelial cell protein antibody Binder of Rho GTPases 5 antibody Bone marrow stromal/endothelial cell protein, 55-KD antibody BORG 5 antibody BORG5 antibody BORG5_HUMAN antibody CDC42 effector pro
- Purification:
- ProA affinity purified
- Background:
- MSE55 also known as Borg5 or binder of Rho GTPases 5 is a Cdc42 effector protein that induces long cellular extensions in fibroblasts. MSE55 also increases and mediates actin cytoskeleton reorganization at the plasma membrane. MSE55 is a nonkinase CRIB (Cdc42/Rac interactive-binding) domain-containing molecule. An intact CRIB domain is required for the GTP-dependent binding of MSE55 to Cdc42. MSE55 is expressed in a tissue-specific manner in endothelial and bone marrow stromal cells. MSE55 may have a functional role in hematopoiesis or as a negative regulator of Rho GTPase signaling.
© Signalway Biotechnology All Rights Reserved.