Product Datasheet
PAX7 Antibody
Catalog Number: 49173
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P23759
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- recombinant protein
- appl_detail:
- WB: 1:1,000
FC: 1:50-1:100
- other_names:
- FLJ37460 antibody HUP1 antibody OTTHUMP00000002534 antibody Paired box 7 antibody Paired box gene 7 antibody Paired box homeotic gene 7 antibody Paired box protein Pax-7 antibody Paired domain gene 7 antibody Paired
- Purification:
- ProA affinity purified
- Background:
- The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).
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