Product Datasheet
CEBP alpha Antibody
Catalog Number: 49157
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P49715
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- recombinant protein
- appl_detail:
- WB: 1:1,000
FC: 1:50-1:100
- other_names:
- Apoptotic cysteine protease antibody Apoptotic protease Mch 5 antibody C/EBP alpha antibody C/ebpalpha antibody CAP4 antibody Caspase 8 precursor antibody CBF-A antibody CCAAT Enhancer Binding Protein alpha antibody
- Purification:
- ProA affinity purified
- Background:
- The transcription factor C/EBP α (CCAAT-enhancer binding protein) is a heat-stable, sequence-specific DNA-binding protein that binds avidly to several different cis-regulatory DNA sequences commonly associated with viral and cellular genes transcribed by RNA polymerase II. C/EBP α regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP α is a basic region/leucine zipper transcription factor selectively expressed during the differentiation of liver, adipose tissue, blood cells and the endocrine pancreas. C/EBP α uses a bipartite structural motif to bind DNA and appears to function exclusively in terminally differentiated, growth-arrested cells. In the liver, C/EBP α is a transactivator of several genes, which are regulated by growth hormone. Growth hormone enhances not only the levels of C/EBP α mRNA and protein, but also the DNA binding activity of C/EBP α. C/EBP α functions as an important transcription factor that regulates different genes, including prolactin gene expression.
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