Product Datasheet  
Kv1.1 potassium channel Antibody  
Catalog Number: 49085  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q09470
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • recombinant protein
  • reactivity:  
  • Hu, Ms, Rt
  • appl_detail:  
  • WB: 1:5,000-1:10,000
    IHC: 1:50-1:200


  • other_names:  
  • AEMK antibody
    EA1 antibody
    Episodic ataxia with myokymia antibody
    HBK1 antibody
    HUK1 antibody
    Kca1 1 antibody
    Kcna1 antibody
    KCNA1_HUMAN antibody
    Kcpvd antibody
    KV1.1 antibody
    MBK1 antibody
    mceph anti
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB, IHC, IP
  • Background:  
  • Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles, and other excitable cells. The KV gene family encodes more than 30 genes that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution, and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming -subunits (KVα), which include the KV1, KV2, KV3, and KV4 proteins, and accessory or KVβ subunits that modify the gating properties of the coexpressed KVα subunits. Differences exist in the patterns of trafficking, biosynthetic processing and surface expression of the major KV1 subunits (KV1.1, KV1.2, KV1.4, KV1.5 and KV1.6) expressed in rat and human brain, suggesting that the individual protein subunits are highly regulated to control for the assembly and formation of functional neuronal channels.



 
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