Product Datasheet  
NSD3 Antibody  
Catalog Number: 49051  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q9BZ95
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • recombinant protein
  • reactivity:  
  • Hu, Ms, Rt
  • appl_detail:  
  • WB: 1:1,000-1:2,000



    FC: 1:50-1:100
  • other_names:  
  • DKFZp667H044 antibody
    FLJ20353 antibody
    Histone lysine N methyltransferase NSD3 antibody
    Histone-lysine N-methyltransferase NSD3 antibody
    MGC126766 antibody
    MGC142029 antibody
    NSD 3 antibody
    NSD3_HUMAN antibody
    Nucl
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB, FC
  • Background:  
  • The deduced 1,437 amino acid NSD3 protein contains two PWWP domains involved in protein-protein interactions, five PHD-type zinc finger motifs found in chromatin-associated proteins, a SAC (SET-associated cys-rich) domain, a SET domain and a C-terminal C5HCH domain. Two NSD3 variants have been identified. The short variant comprised of 645 amino acids, arises from alternative polyadenylation and exon splicing and contains a single PWWP domain. A longer NSD3 variant, which is only expressed in HeLa cells, is comprised of 1,388 amino acid residues. The human WHSC1L1 gene, which encodes the NSD3 protein, shares 68% and 55% identity with mouse Nsd1 and human WHSC1, respectively. Highest expression of NSD3 is observed in brain, heart and skeletal muscle tissues; lower levels of NSD3 expression are observed in the liver and lungs.



 
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