Product Datasheet  
Integrin alpha E Antibody  
Catalog Number: 49038  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P38570
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • recombinant protein
  • reactivity：  
  • Hu
  • appl_detail：  

  • IHC: 1:50-1:200


  • other_names：  
  • A530055J10 antibody
    alpha-E1 antibody
    alpha-M290 antibody
    aM290 antibody
    Antigen CD103 antibody
    CD 103 antibody
    CD103 antibody
    CD103 antigen antibody
    HML 1 antigen antibody
    HML-1 antigen antibody
    HML1 anti
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • IHC
  • Background：  
  • Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.



 
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