Product Datasheet  
IKB beta Antibody  
Catalog Number: 49019  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q15653
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • recombinant protein
  • reactivity：  
  • Hu
  • appl_detail：  
  • WB: 1:1,000
    IHC: 1:50-1:200
    ICC: 1:50-1:200

  • other_names：  
  • I kappa B beta antibody
    I-kappa-B-beta antibody
    IkappaBbeta antibody
    IKB beta antibody
    IkB-B antibody
    IkB-beta antibody
    IKBB antibody
    IKBB_HUMAN antibody
    IkBbeta antibody
    NF kappa BIB antibody
    NF-kappa-B i
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB, ICC, IHC, IP
  • Background：  
  • On the basis of both functional and structural considerations, members of the IkB family of proteins can be divided into four groups. The first of these groups, IkB-α, includes the avian protein pp40 and the mammalian MAD-3, both of which inhibit binding of p50-p65 NFkB complex or Rel protein to their cognate binding sites but do not inhibit the binding of p50 homodimer to kB sites, suggesting that the IkB-α family binds to the p65 subunit of p50-p65 heterocomplex through ankyrin repeats. The second member of the IkB family is represented by a protein designated IkB-β. The third group of IkB proteins is represented by IkB-ε, which is identical in sequence with the C-terminal domain of the p110 precursor of NFkB p50 and is expressed predominantly in lymphoid cells. An additional IkB family member, IkB-, has several phosphorylated forms and is primarily found complexed with Rel A and/or c-Rel.



 
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