Product Datasheet
RALBP1 Antibody
Catalog Number: 49006
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q15311
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- recombinant protein
- appl_detail:
- WB: 1:1,000-5,000
IHC: 1:50-1:200
FC: 1:50-1:100
- other_names:
- RLIP1 antibody
76 kDa Ral-interacting protein antibody
76-kDa Ral-interacting protein antibody
Dinitrophenyl S-glutathione ATPase antibody
DNP-SG ATPase antibody
Ral-interacting protein 1 antibody
Ral-interacting
- Purification:
- ProA affinity purified
- Applications:
- WB, IHC, FC
- Background:
- Ral A and Ral B constitute a distinct subfamily of Ras-related GTPases (i.e., GDP/GTP binding proteins). Ral proteins are activated by a unique nucleotide exchange factor, Ral GDS, and deactivated by a distinct GTPase-activating protein. Unlike Ras proteins, Ral A and Ral B fail to induce transformed foci when activated variants are expressed in various recipient cells. A potential downstream target of Ral, designated Ral BP-1, has been shown to contain a Rho-GTPase-activating domain. This Rho-GTPase-activating domain interacts preferentially with the Rho family member Cdc42. A Ras/Ral signaling pathway has been reported to mediate phospholipase D (PLD) activation by v-Src, thus indicating PLD as another downstream target of Ral A.
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