Product Datasheet
ATG9A Antibody
Catalog Number: 48988
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q7Z3C6
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- recombinant protein
- appl_detail:
- WB: 1:1,000
IHC: 1:50-1:200
ICC: 1:50-1:200
- other_names:
- APG9 autophagy 9-like 1 antibody APG9 like 1 antibody APG9-like 1 antibody APG9L1 antibody ATG9 antibody ATG9 autophagy related 9 homolog A antibody ATG9 autophagy related 9 homolog A (S. cerevisiae) antibody ATG9A antib
- Purification:
- ProA affinity purified
- Applications:
- WB, ICC, IHC, IP
- Background:
- Autophagy, a process that results in the lysosomal-dependent degradation of cytosolic compartments, is carried out by the autophagosome, which is a double-membrane vesicle whose formation is catalyzed by several autophagy-related gene (Atg) proteins. Atg9a (autophagy-related protein 9A), also known as APG9-like 1, is a 839 amino acid, multi-pass membrane protein that localizes to the pre-autophagosomal structure (PAS). Isolation membranes are suggested to originate from the PAS, enwrapping cytoplasmic components to form a double membrane autophagosome, which then fuses with the vacuole. Ubiquitously expressed in human adult tissues, Atg9a cycles between the Golgi and endosomes and, with the autophagosome-specific marker LC3, plays a critical role in starvation-induced autophagosome formation. Three isoforms of Atg9a exist as a result of alternative splicing events.
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