Product Datasheet  
Sonic Hedgehog Protein/SHH(C-Product) Antibody  
Catalog Number: 48975  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q15465
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • recombinant protein
  • reactivity:  
  • Hu
  • appl_detail:  
  • WB: 1:1,000-1:2,000
    IHC: 1:200-1:500
    ICC: 1:50-1:200

    FC: 1:50-1:100
  • other_names:  
  • HHG 1 antibody
    HHG-1 antibody
    HHG1 antibody
    HLP 3 antibody
    HLP3 antibody
    Holoprosencephaly 3 antibody
    HPE 3 antibody
    HPE3 antibody
    MCOPCB5 antibody
    shh antibody
    SHH_HUMAN antibody
    SMMC I antibody
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB, ICC/IF, IHC, FC
  • Background:  
  • The Drosophila segment polarity gene hedgehog (hh) encodes a precursor protein which undergoes autocleavage to generate amino- and carboxy-terminal peptides. Both proteins are secreted and appear to function in embryonic and imaginal disc patterning. Several vertebrate homologs of Drosophila hh have been identified. These include Sonic hedgehog (Shh) (alternatively designated Vhh-1), Desert hedgehog (Dhh) and Indian hedgehog (Ihh). Each contain amino-terminal signal peptides and apparently function as secreted proteins involved in the mediation of various cell-cell interactions. Shh resembles Drosophila hh in that it is processed to generate an amino-terminal secreted peptide that is retained at or near the cell surface and a carboxy-terminal glycosylated more diffusible peptide.



 
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