Product Datasheet  
IKK gamma Antibody  
Catalog Number: 49550  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q9Y6K9
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • recombinant protein
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  
  • WB: 1:500-1:2,000
    IHC: 1:20-1:50
    ICC: 1:50-1:200

    FC: 1:50-1:100
  • other_names：  
  • IkB kinase associated protein 1 antibody
    IkB kinase subunit gamma antibody
    Inhibitor of nuclear factor kappa B kinase subunit gamma antibody
    AMCBX1 antibody
    FIP 3 antibody
    FIP-3 antibody
    FIP3 antibody
    Fip3p
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB, IHC, ICC/IF, IP, FC
  • Background：  
  • Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'-linked or linear polyubiquitin) and its functional importance is reported conflictingly. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral innate response; this function requires 'Lys-27'-linked polyubiquitination.



 
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