Product Datasheet
Acetyl CoA synthetase Antibody
Catalog Number: 49335
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9NR19
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- recombinant protein
- appl_detail:
- WB: 1:1,000
ICC: 1:50-1:200
- other_names:
- ACAS2 antibody AceCS antibody Acetate CoA ligase antibody Acetate thiokinase antibody Acetate--CoA ligase antibody Acetyl CoA synthetase antibody Acetyl Coenzyme A synthetase 2 (ADP forming) antibody Acetyl coenzyme A sy
- Purification:
- ProA affinity purified
- Background:
- ACSS2 (acyl-CoA synthetase short-chain family member 2), also known as ACAS2, ACS, ACSA or AceCS, is a 701 amino acid cytoplasmic protein that belongs to the ATP-dependent AMP-binding enzyme family. Existing as a monomer, ACSS2 functions to catalyze the ATP-dependent activation of acetate, a reaction that yields acetyl-CoA for use in energy generation and lipid synthesis. ACSS2 expression, which is highest in liver and kidney tissue, is regulated by the presence of unsaturated fatty acids and sterol regulatory element-binding proteins (SREBPs). Human ACSS2 exists as two alternatively spliced isoforms and shares 93% sequence identity with its mouse counterpart, suggesting a conserved role between species.
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