Product Datasheet
PIM1 Antibody
Catalog Number: 48894
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P11309
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- recombinant protein
- appl_detail:
- WB: 1:1,000-1:2,000
IHC: 1:50-1:200
ICC: 1:50-1:200
- other_names:
- Oncogene PIM 1 antibody Oncogene PIM1 antibody PIM 1 antibody pim 1 kinase 44 kDa isoform antibody Pim 1 kinase antibody pim 1 oncogene (proviral integration site 1) antibody Pim 1 oncogene antibody PIM antibody PIM
- Purification:
- ProA affinity purified
- Applications:
- WB, ICC/IF, IHC
- Background:
- Pim-1 is a serine/threonine kinase that cooperates with c-Myc in lymphoid cell transformation. The expression of pim-1 increases during the progression from early to late G1, remaining high at the G1/S boundary and G2 phases of the cell cycle. Pim-1 is regulated at both the transcriptional and translational level, and it has been shown to be induced by IL-2 stimulation. Pim-1 also plays a role in T cell differentiation, and it has been shown to stimulate c-Myc-mediated apoptosis upstream of caspase-3-like proteases.
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