Product Datasheet  
Stathmin 1 Antibody  
Catalog Number: 48859  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:P16949
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • recombinant protein
  • reactivity:  
  • Hu, Ms, Rt
  • appl_detail:  
  • WB: 1:1,000-1:2,000
    IHC: 1:50-1:200
    ICC: 1:100-1:500

    FC: 1:50-1:100
  • other_names:  
  • C1orf215 antibody
    Lag antibody
    LAP 18 antibody
    LAP18 antibody
    Leukemia associated phosphoprotein p18 antibody
    Leukemia-associated phosphoprotein p18 antibody
    Metablastin antibody
    Oncoprotein 18 antibody
    OP 18 antibo
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB, ICC, IHC, IP, FC
  • Background:  
  • Op18 (for oncoprotein 18, also designated stathmin, prosolin or metablastin) is a conserved, tubulin-associated, intracellular phosphoprotein . Many different phosphorylated forms of Op18 are observed, and it is expressed as two different isoforms. Op18 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phophorylation, for a variety of cell signaling pathways and involved in both mitosis and differentiation. Op18 is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.



 
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