Product Datasheet  
MCSF Antibody  
Catalog Number: 48850  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:P09603
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • recombinant protein
  • reactivity:  
  • Hu
  • appl_detail:  
  • WB: 1:500-1:1000
    IHC: 1:50-1:100
    ICC: 1:50-1:200

  • other_names:  
  • Colony stimulating factor 1 (macrophage) antibody
    Colony stimulating factor 1 antibody
    Colony stimulating factor macrophage specific antibody
    CSF 1 antibody
    CSF-1 antibody
    CSF1 antibody
    CSF1_HUMAN antibody
    Csfm antibody<
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB, IHC, ICC, IP
  • Background:  
  • The macrophage colony-stimulating factor (M-CSF), also designated CSF-1, was originally discovered in serum, urine and other biological fluids as a factor that can stimulate the formation of macrophage colonies from bone marrow hematopoietic progenitor cells. M-CSF is a homodimeric cytokine that is produced by fibroblasts, epithelial cells, bone marrow stromal cells, osteoblasts, keratinocytes, macrophages, T cells and B cells. M-CSF is a glycoprotein required for the proliferation and differentiation of mononuclear phagocytes, including osteoclasts. M-CSF has also been identified as an important mediator of the inflammatory response and can regulate the release of proinflammatory cytokines from macrophages. M-CSF exerts its pleiotropic effects by binding to a single type of high affinity cell surface receptor that is encoded by the c-Fms proto-oncogene.



 
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