Product Datasheet
Lactate Dehydrogenase Antibody
Catalog Number: 48839
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P00338
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- recombinant protein
- reactivity:
- Hu, Ms, Rt, zebrafish
- appl_detail:
- WB: 1:1,000-5,000
IHC: 1:200-1:500
ICC: 1:50-1:200
FC: 1:50-1:100
- other_names:
- Cell proliferation-inducing gene 19 protein antibody
GSD11 antibody
L lactate dehydrogenase B chain antibody
L-lactate dehydrogenase A chain antibody
Lactate dehydrogenase A antibody
Lactate dehydrogenase B antibody
- Purification:
- ProA affinity purified
- Applications:
- WB, ICC/IF, IHC, IP, FC
- Background:
- The lactate dehydrogenase family (LDH) catalyzes the final step of anaerobic glycolysis, the conversion of L-lactate and NAD to pyruvate and NADH. The LDH family consists of three members, LDH-A, LDH-B and LDH-C, all of which form tetramers consisting four subunits. However, each family member displays a specific tissue distribution pattern with LDH-A and LDH-B predominant in several tissues, specifically LDH-A in muscle and LDH-B in heart, while LDH-C expression is confined to the testis and sperm. LDHs function as powerful markers for germ cell tumors. The genes encoding human LDH-A and LDH-C map to chromosome 11, while the human LDH-B gene maps to chromosome 12. Deficiency in the LDH-A gene is linked to exertional myoglobinuria.
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