Product Datasheet  
alpha smooth muscle Actin Antibody  
Catalog Number: 48790  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:P62736
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • recombinant protein
  • reactivity:  
  • Hu, Ms, Rt
  • appl_detail:  
  • WB: 1:1,000-1:2,000
    IHC: 1:50-1:200
    ICC: 1:100-1:500

    FC: 1:50-1:100
  • other_names:  
  • a actin antibody
    AAT6 antibody
    ACTA_HUMAN antibody
    ACTA2 antibody
    Actin alpha 2 smooth muscle aorta antibody
    Actin aortic smooth muscle antibody
    Actin, aortic smooth muscle antibody
    ACTSA antibody
    ACTVS antibody
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB, ICC/IF, IHC, FC
  • Background:  
  • All eukaryotic cells express Actin, which often constitutes as much as 50% of total cellular protein. Actin filaments can form both stable and labile structures and are crucial components of microvilli and the contractile apparatus of muscle cells. While lower eukaryotes, such as yeast, have only one Actin gene, higher eukaryotes have several isoforms encoded by a family of genes. At least six types of Actin are present in mammalian tissues and fall into three classes. α-Actin expression is limited to various types of muscle, whereas β-Actin and γ-Actin are the principle constituents of filaments in other tissues. Members of the small GTPase family regulate the organization of the Actin cytoskeleton. Rho controls the assembly of Actin stress fibers and focal adhesion. Rac regulates Actin filament accumulation at the plasma membrane. Cdc42 stimulates formation of filopodia.



 
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