Product Datasheet
Musashi 1 Antibody
Catalog Number: 48764
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q07954
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- recombinant protein
- appl_detail:
- WB: 1:1000
IHC: 1:50-1:200
ICC: 1:50-1:200
FC: 1:50-1:200
- other_names:
- Msi 1 antibody
Msi1 antibody
MSI1H_HUMAN antibody
Musashi homolog 1 antibody
Musashi-1 antibody
Musashi1 antibody
RNA binding protein Musashi homolog 1 antibody
RNA-binding protein Musashi homolog 1 antibod
- Purification:
- ProA affinity purified
- Applications:
- WB, ICC/IF, IHC, IP, FC
- Background:
- Musashi1 (Msi1) is an RNA-binding protein expressed in neural progenitor cells and neural stem cells. Msi1 is the mammalian homolog of Drosophila Musashi. The gene encoding human Msi1 encodes a 362 amino acid protein. In murine embryonic neural progenitor cells, Msi1 localizes to the cytoplasm and is downregulated during differentiation. Msi1 binds to NUMB, which encodes a membrane-associated antagonist of Notch signaling. Msi1 appears to function in the proliferation and maintenance of stem cell populations of the central nervous system. In addition to its usefulness as a marker for neural progenitor cells in normal human brains, Msi1 is also a marker for human gliomas. In rats, Msi1 is expressed in Sertoli cells of the testis and granulosa cells of the ovary.
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