Product Datasheet  
CD20 Antibody  
Catalog Number: 48726  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P11836
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • recombinant protein
  • reactivity：  
  • Hu, Monkey
  • appl_detail：  
  • WB: 1:1,000-5,000
    IHC: 1:50-1:200


  • other_names：  
  • APY antibody
    ATOPY antibody
    B lymphocyte antigen CD20 antibody
    B Lymphocyte Cell Surface Antigen B1 antibody
    B-lymphocyte antigen CD20 antibody
    B-lymphocyte cell-surface antigen B1 antibody
    B-lymphocyte surface an
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB, IHC, IP
  • Background：  
  • CD20 is a leukocyte surface antigen consisting of four transmembrane regions and cytoplasmic N- and C-termini. The cytoplasmic domain of CD20 contains multiple phosphorylation sites, leading to additional isoforms. CD20 is expressed primarily on B cells but has also been detected on both normal and neoplastic T cells. CD20 functions as a calcium-permeable cation channel, and it is known to accelerate the G0 to G1 progression induced by IGF-1. CD20 is activated by the IGF-1 receptor via the alpha subunits of the heterotrimeric G proteins. Activation of CD20 significantly increases DNA synthesis and is thought to involve basic helix-loop-helix leucine zipper transcription factors.



 
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