Product Datasheet  
p53 Antibody  
Catalog Number: 48599  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P04637
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • recombinant protein
  • reactivity：  
  • Hu, Zebrafish
  • appl_detail：  
  • WB: 1:1,000-5,000

    ICC: 1:50-1:200

  • other_names：  
  • Antigen NY-CO-13 antibody
    BCC7 antibody
    Cellular tumor antigen p53 antibody
    FLJ92943 antibody
    LFS1 antibody
    Mutant tumor protein 53 antibody
    p53 antibody
    p53 tumor suppressor antibody
    P53_HUMAN antib
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB, ICC/IF
  • Background：  
  • The p53 tumor suppressor protein plays a major role in cellular response to DNA damage and other genomic aberrations. Activation of p53 can lead to either cell cycle arrest and DNA repair or apoptosis. It is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro. P53 is found in increased amounts in a wide variety of transformed cells. P53 is frequently mutated or inactivated in about 60% of cancers.



 
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