Product Datasheet
ZO1 Antibody
Catalog Number: 48588
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q07157
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- appl_detail:
IHC: 1:200
ICC: 1:200
- other_names:
- Tight junction protein 1 antibody Tight junction protein ZO-1 antibody Tight junction protein ZO1 antibody TJP1 antibody zo-1 antibody Zo1 antibody ZO1_HUMAN antibody Zona occludens 1 antibody Zona occludens 1 prote
- Purification:
- Peptide affinity purified
- Background:
- Tight junction protein ZO-1 is a protein that in humans is encoded by the TJP1 gene. This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. ZO1 plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.
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