Product Datasheet
STAT6 Antibody
Catalog Number: 48579
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P42226
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- appl_detail:
- WB: 1:1,000
IHC: 1:200
ICC: 1:200
FC: 1:100-1:200
- other_names:
- 12S1644 antibody
D12S1644 antibody
IL 4 STAT antibody
IL-4 Stat antibody
IL4 STAT antibody
Interleukin 4 Induced antibody
Interleukin 4 Induced Transcription Factor IL4 STAT antibody
Signal transducer and a
- Purification:
- Peptide affinity purified
- Applications:
- WB, ICC, IHC, FC
- Background:
- In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein STAT6 plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2), expression of cell surface markers, and class switch of immunoglobulins.
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