Product Datasheet  
Integrin beta-1/CD29 Antibody  
Catalog Number: 48565  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P05556
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • peptide
  • reactivity：  
  • Hu, Ms
  • appl_detail：  
  • WB: 1:500-1:1000
    IHC: 1:200


    FC: 1:100
  • other_names：  
  • beta1 integrin antibody
    CD29 antibody
    Fibronectin receptor subunit beta antibody
    FNRB antibody
    Glycoprotein IIa antibody
    GP IIa antibody
    GPIIA antibody
    Integrin beta-1 antibody
    integrin VLA-4 beta subunit antibody
  • Purification：  
  • Peptide affinity purified
  • Specificity：  
  • Applications：  
  • WB, IHC, FC
  • Background：  
  • Integrins are transmembrane receptors that mediate the attachment between a cell and its surroundings, such as other cells or the extracellular matrix (ECM). Integrins are obligate heterodimers containing two distinct chains, called the α (alpha) and β (beta) subunits. The molecular mass of the integrin subunits can vary from 90?kDa to 160?kDa. Beta subunits have four cysteine-rich repeated sequences. Both α and β subunits bind several divalent cations. Integrins have two main functions: Attachment of the cell to the ECM and signal transduction from the ECM to the cell. However, they are also involved in a wide range of other biological activities, including immune patrolling, cell migration, and binding to cells by certain viruses, such as adenovirus, echovirus, hantavirus, and foot and mouth disease viruses. Research studies have implicated β1 integrin in various activities including embryonic development, blood vessel, skin, bone, and muscle formation, as well as tumor metastasis and angiogenesis.



 
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