Product Datasheet  
IL1 alpha Antibody  
Catalog Number: 48528  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P01583
  • Form of Antibody：  
  • 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein
  • reactivity：  
  • Hu, Ms
  • appl_detail：  

  • IHC: 1:400-1:800


    FC: 1:50-1:100
  • other_names：  
  • BAF antibody
    FAF antibody
    Hematopoietin 1 antibody
    Hematopoietin-1 antibody
    IL 1 alpha antibody
    IL 1A antibody
    IL-1 alpha antibody
    Il-1a antibody
    IL1 ALPHA antibody
    IL1 antibody
  • Purification：  
  • Protein affinity purified
  • Specificity：  
  • Applications：  
  • IHC,FC,WB
  • Background：  
  • Two forms of interleukin-1, designated IL-1α and IL-1β, have been described. Although encoded by distinct genes and exhibiting roughly only 25% sequence identity, IL-1α and IL-1β bind to the same receptor and seem to elicit similar biological responses. IL-1 production is generally thought to be associated with inflammation, but it has also been shown to be expressed during kidney development, thymocyte differentiation and cartilage degradation. IL-1 plays a critical role in the regulation of immune response and inflammation, acting as an activator of T and B lymphocytes and natural killer (NK) cells. In T cells, IL-1 stimulates the production of IL-2 and selectively inhibits IL-4 expression. IL-1 induces B cell proliferation and maturation, and immunoglobulin synthesis. NK cells require IL-1β for production of the anti- pathogen IFN-γ. IL-1 has also been implicated in several pathological conditions including rheumatoid arthritis, inflammatory bowel disease and atherosclerosis.



 
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