Product Datasheet
ZBTB48 Antibody
Catalog Number: 48518
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P10074
- Form of Antibody:
- 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
- appl_detail:
- WB: 1:500-1:1,000
IHC: 1:50-1:200
ICC: 1:50-1:200
FC: 1:50-1:200
- other_names:
- 0610011D15Rik antibody
AI327031 antibody
GLI Kruppel family member HKR3 antibody
HKR3 antibody
Krueppel related zinc finger protein 3 antibody
Krueppel-related zinc finger protein 3 antibody
OTTMUSP00000031803 a
- Purification:
- Peptide affinity purified
- Applications:
- WB,ICC,IHC,FC
- Background:
- Telomere-binding protein that acts as a regulator of telomere length. Directly binds the telomeric double-stranded 5'-TTAGGG-3' repeat. Preferentially binds to telomeres that have a low concentration of shelterin complex and acts as a regulator of telomere length by initiating telomere trimming, a process that prevents the accumulation of aberrantly long telomeres. Also acts as a transcription regulator that binds to promoter regions. Regulates expression of a small subset of genes, including MTFP1. Regulates expression the J and/or S elements in MHC II promoter. Acts as a negative regulator of cell proliferation by specifically activating expression of ARF, a tumor suppressor isoform of CDKN2A.
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