Product Datasheet  
Bcl-2 Antibody  
Catalog Number: 48496  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P10415
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide (KLH-coupled) within human Bcl-2 aa 20-80.
  • reactivity：  
  • Hu
  • appl_detail：  
  • WB: 1:500
    IHC: 1:200
    ICC: 1:200

    FC: 1:50-1:100
  • other_names：  
  • Apoptosis regulator Bcl 2 antibody
    Apoptosis regulator Bcl-2 antibody
    Apoptosis regulator Bcl2 antibody
    AW986256 antibody
    B cell CLL/lymphoma 2 antibody
    B cell leukemia/lymphoma 2 antibody
    Bcl-2 antibody
    Bc
  • Purification：  
  • Peptide affinity purified
  • Specificity：  
  • Applications：  
  • WB, ICC, IHC, FC
  • Background：  
  • Damage to the Bcl-2 gene has been identified as a cause of a number of cancers, including melanoma, breast, prostate, chronic lymphocytic leukemia, and lung cancer, and a possible cause of schizophrenia and autoimmunity. It is also a cause of resistance to cancer treatments. Antibodies to Bcl-2 can be used with immunohistochemistry to identify cells containing the antigen. In healthy tissue, these antibodies will react with B-cells in the mantle zone, as well as some T-cells. However, there is a considerable increase in positive cells in follicular lymphoma, as well as many other forms of cancer. In some cases, the presence or absence of Bcl-2 staining in biopsies may be significant for the patient's prognosis or likelihood of relapse.



 
© Signalway Biotechnology All Rights Reserved.