Product Datasheet
LDHA Antibody
Catalog Number: 48492
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P00338
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- appl_detail:
- WB: 1:500
IHC: 1:200
FC: 1:100-1:200
- other_names:
- Cell proliferation-inducing gene 19 protein antibody GSD11 antibody L lactate dehydrogenase A chain antibody L-lactate dehydrogenase A chain antibody l7R2 antibody Lactate dehydrogenase 1, A chain antibody Lactate dehydrogena
- Purification:
- Peptide affinity purified
- Applications:
- WB, IHC, FC
- Background:
- Lactate dehydrogenase (LDH) is an enzyme present in a wide variety of organisms, including plants and animals. It catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. In medicine, LDH is often used as a marker of tissue breakdown as LDH is abundant in red blood cells and can function as a marker for hemolysis. In mammals, three types of LDH subunits (35 kDa) are encoded by the genes Ldh-A, Ldh-B, and Ldh-C. Lactate dehydrogenase B (LDH-B, heart subunit, LDH-H) is involved in the conversion of L-lactate and NAD to pryruvate and NADH and it is predominantly localized in the heart tissue. Similar to other LDH subunit, LDH-B is considered to be an important marker for germ cell tumor.
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