Product Datasheet  
SNAP-25 Antibody  
Catalog Number: 48267  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:P60880
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • peptide
  • reactivity:  
  • Hu, Ms, Rt
  • appl_detail:  
  • WB: 1:1,000

    ICC: 1:100
    IP: 1:10-100
  • other_names:  
  • bA416N4.2 antibody
    Bdr antibody
    CMS18 antibody
    dJ1068F16.2 antibody
    FLJ23079 antibody
    HGNC:11132 antibody
    MGC105414 antibody
    MGC139754 antibody
    Resistance to inhibitors of cholinesterase 4 homolog an
  • Purification:  
  • Protein A purified
  • Specificity:  
  • Applications:  
  • WB, ICC/IF, IP
  • Background:  
  • Syntaxins were originally thought to be docking proteins, but have now been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins have been shown to bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF (N-ethylmaleimide-sensitive factor), SNAP 25, SNAPs (soluble NSF attachment proteins) and synaptotagmin. VAMPs, also designated synaptobrevins, including VAMP-1 and VAMP-2, and synaptotagmin, a protein that may function as an inhibitor of exocytosis, are vesicular proteins. SNAPs, including α- and γ-SNAP, are cytoplasmic proteins that bind to a membrane receptor complex composed of VAMP, SNAP 25 and syntaxin. SNAPs mediate the membrane binding of NSF, which is essential for membrane fusion reactions. An additional protein designated synaptophysin may regulate exocytosis by competing with SNAP 25 and syntaxins for VAMP binding.



 
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