Product Datasheet
SNAP-25 Antibody
Catalog Number: 48267
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P60880
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- appl_detail:
- WB: 1:1,000
ICC: 1:100
IP: 1:10-100
- other_names:
- bA416N4.2 antibody
Bdr antibody
CMS18 antibody
dJ1068F16.2 antibody
FLJ23079 antibody
HGNC:11132 antibody
MGC105414 antibody
MGC139754 antibody
Resistance to inhibitors of cholinesterase 4 homolog an
- Purification:
- Protein A purified
- Applications:
- WB, ICC/IF, IP
- Background:
- Syntaxins were originally thought to be docking proteins, but have now been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins have been shown to bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF (N-ethylmaleimide-sensitive factor), SNAP 25, SNAPs (soluble NSF attachment proteins) and synaptotagmin. VAMPs, also designated synaptobrevins, including VAMP-1 and VAMP-2, and synaptotagmin, a protein that may function as an inhibitor of exocytosis, are vesicular proteins. SNAPs, including α- and γ-SNAP, are cytoplasmic proteins that bind to a membrane receptor complex composed of VAMP, SNAP 25 and syntaxin. SNAPs mediate the membrane binding of NSF, which is essential for membrane fusion reactions. An additional protein designated synaptophysin may regulate exocytosis by competing with SNAP 25 and syntaxins for VAMP binding.
© Signalway Biotechnology All Rights Reserved.