Product Datasheet  
ICAM-1 Antibody  
Catalog Number: 48266  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P05362
  • Form of Antibody：  
  • 1*TBS (pH7.4),1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • peptide
  • reactivity：  
  • Hu
  • appl_detail：  
  • WB: 1:1,000
    IHC: 1:100


  • other_names：  
  • Antigen identified by monoclonal antibody
    BB2 antibody
    BB 2 antibody
    BB2 antibody
    CD 54 antibody
    CD_antigen=CD54 antibody
    CD54 antibody
    Cell surface glycoprotein P3.58 antibody
    Human rhinovirus recep
  • Purification：  
  • Protein A purified
  • Specificity：  
  • Applications：  
  • WB, IHC
  • Background：  
  • Antigen-specific cell contacts in the immune system are strengthened by antigen-nonspecific interactions, mediated in part by lymphocyte-function associated (LFA) antigens. Recently, ICAM-1 (intercellular adhesion molecule-1) has been defined as a ligand for LFA-1. Monoclonal antibodies to ICAM-1 block T lymphocyte adhesion to fibroblasts and endothelial cells and disrupt the interaction between cytotoxic T cells and target cells. ICAM-1 is found on leukocytes, fibroblasts, epithelial cells and endothelial cells and its expression is regulated by inflammatory cytokines. The normal function of human ICAM-1 is to provide adhesion between endothelial cells and leukocytes after injury or stress. However, ICAM-1 is also used as a receptor by the major group of human rhinoviruses and is a catalyst for the subsequent viral uncoating during cell entry. Monoclonal antibodies recognize a 95 kDa cell surface glycoprotein the major human rhinovirus receptor, ICAM-1



 
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