Product Datasheet  
Estrogen Receptor alpha Antibody  
Catalog Number: 48263  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P03372
  • Form of Antibody：  
  • 1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • peptide
  • reactivity：  
  • Hu, Baboon
  • appl_detail：  
  • WB: 1:500-1:1000
    IHC: 1:500-1000


  • other_names：  
  • DKFZp686N23123 antibody
    ER alpha antibody
    ER antibody
    ER-alpha antibody
    Era antibody
    ESR antibody
    ESR1 antibody
    ESR1_HUMAN antibody
    ESRA antibody
    Estradiol receptor antibody
    Estrogen nuclear receptor alpha
  • Purification：  
  • Tissue culture supernatant
  • Specificity：  
  • Applications：  
  • WB, IHC
  • Background：  
  • Estrogen receptor alpha (ER alpha) is a nuclear protein and member of the steroid hormone receptor family. ER alpha possesses both DNA binding and ligand binding domains, and exerts a significant role in activating the transcription of certain genes (1). Ligand-dependent dimerization and phosphorylation both function to regulate the transcriptional activation of ER alpha (2). The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy (3).



 
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