Product Datasheet  
Bcl-x Antibody  
Catalog Number: 48262  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q07817
  • Form of Antibody：  
  • 1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • peptide
  • reactivity：  
  • Hu,Ms,Rt
  • appl_detail：  
  • WB: 1:500-1,000
    IHC: 1:50-100
    ICC: 1:100
    IP: 1:10
    FC: 1:50
  • other_names：  
  • Apoptosis regulator Bcl X antibody
    Bcl 2 like 1 antibody
    Bcl 2 like 1 protein antibody
    Bcl xL antibody
    BCL XL/S antibody
    Bcl xS antibody
    Bcl2 like1 antibody
    BCL2-related gene antibody
    BCL2-related protein, long isof
  • Purification：  
  • Protein A purified
  • Specificity：  
  • Applications：  
  • WB, ICC, IHC, FC, IP
  • Background：  
  • Bcl-x, a member of the Bcl-2 protein family, inhibits cell death, or apoptosis (1). Bcl-x is expressed as two isomeric forms, Bcl-xL and Bcl-xS, and is typically present in the cytosol in association with the mitochondrial membrane. Bcl-xL forms heterodimers with various proteins, including Bax, Bak and Bcl-2 (2). It has been found that heterodimerization with Bax does not seem to be required for anti-apoptotic activity (3). Since Bcl-xL can form an ion channel in synthetic lipid membranes, there is a strong possibility that this property plays a role in heterodimerization-independent cell survival (4). The Bcl-X(S) isoform promotes apoptosis.



 
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