Product Datasheet  
eIF-4E Antibody  
Catalog Number: 48249  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P06730
  • Form of Antibody：  
  • 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Peptide
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  
  • WB: 1:500-1:1,000 FC: 1:50-1:100

    IHC: 1:50-1:100
    ICC: 1:50-1:200

    FC: 1:50-1:100
  • other_names：  
  • AUTS19 antibody
    CBP antibody
    eIF 4E antibody
    eIF 4F 25 kDa subunit antibody
    EIF 4F antibody
    eIF-4E antibody
    eIF-4F 25 kDa subunit antibody
    eIF4E antibody
    EIF4E1 antibody
    EIF4EL1
  • Purification：  
  • Peptide affinity purified
  • Specificity：  
  • Applications：  
  • WB, ICC, IHC, FC
  • Background：  
  • The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex eIF4F exists in vitro as a trimeric complex of eIF4E, eIF4A and eIF4G. Together, the complex allows ribosome binding to mRNA by inducing the unwinding of mRNA secondary structures. eIF4E binds to the mRNA "cap" during an early step in the initiation of protein synthesis. eIF4A acts as an ATP-dependent RNA helicase. eIF4G acts as a bridge between eIF4E, eIF4A and the eIF3 complex.



 
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