Product Datasheet  
Beclin 1 Antibody  
Catalog Number: 48222  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q14457
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide (KLH-coupled) within human Beclin 1 aa 380-450.
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  

  • IHC: 1:200
    ICC: 1:50-1:100

  • other_names：  
  • APG6 antibody
    ATG 6 antibody
    ATG6 antibody
    ATG6 autophagy related 6 homolog antibody
    Bcl-2-interacting protein beclin antibody
    Beclin 1 (coiled coil moesin like BCL2 interacting protein) antibody
    Beclin 1 autophag
  • Purification：  
  • Peptide affinity purified
  • Specificity：  
  • Applications：  
  • ICC, IHC
  • Background：  
  • Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms. Involved in endocytosis. Protects against infection by a neurovirulent strain of Sindbis virus. May play a role in antiviral host defense.



 
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