Product Datasheet  
PSD95 Antibody  
Catalog Number: 48221  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P78352
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • peptide
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  
  • WB: 1:1000
    IHC: 1:50


  • other_names：  
  • Discs large homolog 4 antibody
    Disks large homolog 4 antibody
    DLG 4 antibody
    Dlg4 antibody
    DLG4_HUMAN antibody
    FLJ97752 antibody
    FLJ98574 antibody
    Human post synaptic density protein 95 antibody
    Post synaptic densit
  • Purification：  
  • Peptide affinity purified
  • Specificity：  
  • Applications：  
  • WB, IHC, FC
  • Background：  
  • PSD-95 is a member of the membrane-associated guanylate kinase(MAGUK) family. With PSD-93 it is recruited into the same NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the?clustering of receptors, ion channels, and associated signaling proteins.PSD-95 is the best studied member of the MAGUK-family of PDZ domain-containing proteins. Like all MAGUK-family proteins, its basic structure includes three PDZ domains, an SH3 domain, and a guanylate kinase-like domain (GK) connected by disordered linker regions. It is almost exclusively located in the post synaptic density ofneurons,and is involved in anchoring synaptic proteins. Its direct and indirect binding partners include neuroligin,NMDA receptors,AMPA receptors, and potassium channels.It plays an important role in synaptic plasticity and the stabilization of synaptic changes during?long-term potentiation.



 
© Signalway Biotechnology All Rights Reserved.