Product Datasheet
eNOS Antibody
Catalog Number: 48217
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P29474
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- appl_detail:
IHC: 1:50-1:100
- other_names:
- Constitutive NOS antibody
EC NOS antibody
EC-NOS antibody
ecNOS antibody
Endothelial nitric oxidase synthase antibody
Endothelial nitric oxide synthase antibody
Endothelial nitric oxide synthase 3 antibody
- Purification:
- ProA affinity purified
- Background:
- Endothelial NOS (eNOS), also known as nitric oxide synthase 3 (NOS3), generates NO in blood vessels and is involved with regulating vascular function. The gene coding for eNOS is located on Chromosome 7. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. A constitutive Ca2+ dependent NOS provides a basal release of NO. eNOS is associated with "caveolae" a component of plasma membranes surrounding cells, and the membranes of Golgi bodies within cells. eNOS localisation to endothelial membranes is mediated by cotranslational N-terminal myristoylation and post-translational palmitoylation.
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