Product Datasheet  
ERP72 Antibody  
Catalog Number: 48212  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:P13667
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • peptide
  • reactivity:  
  • Hu, Ms, Rt
  • appl_detail:  
  • WB: 1:5,000



  • other_names:  
  • Calcium binding protein intestinal related antibody
    Endoplasmic reticulum resident protein 70 antibody
    Endoplasmic reticulum resident protein 72 antibody
    EPR70 antibody
    EPR72 antibody
    ER protein 70 antibody
    ER protein 72 anti
  • Purification:  
  • Peptide affinity purified
  • Specificity:  
  • Applications:  
  • WB, ICC, IHC
  • Background:  
  • Protein disulfide isomerase or PDI is an enzyme in the endoplasmic reticulum in eukaryotes that catalyzes the formation and breakage of disulfide bonds between cysteine residues within proteins as they fold. PDI contains four thioredoxin-like domains, two of which retain the canonical CXXC motif. The reduced (that is, dithiol) form of PDI is able to catalyse a reduction of mispaired thiol residues of a particular substrate, acting as an isomerase. Another major function of PDI relates to its activity as a chaperone; i.e., it aids wrongly folded proteins to reach a correctly folded state without the aid of enzymatic disulfide shuffling. PDI helps load antigenic peptides into MHC class I molecules. These molecules (MHC I) are related to the peptide presentation by antigen-presenting cells in the immune response.



 
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