Product Datasheet
Monoamine oxidase A Antibody
Catalog Number: 48211
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P21397
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- recombinant protein
- appl_detail:
- WB: 1:1000-1:2,000
- other_names:
- Amine oxidase [flavin containing] A antibody Amine oxidase [flavin-containing] A antibody AOFA antibody AOFA_HUMAN antibody EC 1.4.3.4 antibody MAO A antibody MAO-A antibody maoA antibody Monoamine oxidase A antibod
- Purification:
- Peptide affinity purified
- Background:
- Monoamine oxidase A is an enzyme that degrades amine neurotransmitters, such as dopamine, norepinephrine, and serotonin. The protein localizes to the outer mitochondrial membrane. Its encoding gene is adjacent to a related gene (MAOB) on the opposite strand of the X chromosome. MAO-A levels in the brain as measured using positron emission tomography are elevated by an average of 34% in patients with major depressive disorder. Genetic association studies examining the relationship between high-activity MAOA variants and depression have produced mixed results, with some studies linking the high-activity variants to major depression in females, depressed suicide in males, major depression and sleep disturbance in males and major depressive disorder in both males and females.
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