Product Datasheet  
DPY30 Antibody  
Catalog Number: 48183  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q9C005
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • recombinant protein
  • reactivity：  
  • Hu,Ms
  • appl_detail：  

  • IHC: 1:100-1:200
    ICC: 1:100-1:200

  • other_names：  
  • Dpy-30-like protein antibody
    Dpy-30L antibody
    DPY30 antibody
    DPY30_HUMAN antibody
    HDPY-30 antibody
    Protein dpy-30 homolog antibody
    Saf19 antibody
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • ICC, IHC
  • Background：  
  • As part of the MLL1/MLL complex, DPY30 is involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. DPY30 may play some role in histone H3 acetylation. In a teratocarcinoma cell, it plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. DPY30 may also play an indirect or direct role in endosomal transport. In the recent study, it showed that depletion of Dpy-30 does not affect ESC self-renewal, but significantly alters the differentiation potential of ESCs, particularly along the neural lineage.



 
© Signalway Biotechnology All Rights Reserved.