Product Datasheet
TRAF6 Antibody
Catalog Number: 48177
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9Y4K3
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- reactivity:
- Hu, Ms, Rt, Hybrid fish (crucian-carp)
- appl_detail:
- WB: 1:500-1:1,000
ICC: 1:100-1:200
- other_names:
- E3 ubiquitin-protein ligase TRAF6 antibody
Interleukin 1 signal transducer antibody
Interleukin-1 signal transducer antibody
MGC 3310 antibody
MGC:3310 antibody
MGC3310 antibody
OTTHUMP00000232772 antibody
- Purification:
- Peptide affinity purified
- Background:
- TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein mediates the signaling not only from the members of the TNF receptor superfamily, but also from the members of the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/TRANCE/RANKL and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines.
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