Product Datasheet  
TRAF6 Antibody  
Catalog Number: 48177  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q9Y4K3
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • peptide
  • reactivity:  
  • Hu, Ms, Rt, Hybrid fish (crucian-carp)
  • appl_detail:  
  • WB: 1:500-1:1,000

    ICC: 1:100-1:200

  • other_names:  
  • E3 ubiquitin-protein ligase TRAF6 antibody
    Interleukin 1 signal transducer antibody
    Interleukin-1 signal transducer antibody
    MGC 3310 antibody
    MGC:3310 antibody
    MGC3310 antibody
    OTTHUMP00000232772 antibody
  • Purification:  
  • Peptide affinity purified
  • Specificity:  
  • Applications:  
  • ICC, IHC
  • Background:  
  • TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein mediates the signaling not only from the members of the TNF receptor superfamily, but also from the members of the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/TRANCE/RANKL and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines.



 
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