Product Datasheet
VDAC1 Antibody
Catalog Number: 48153
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P21796
- Form of Antibody:
- 1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- reactivity:
- Hu, zebrafish
- appl_detail:
- WB: 1:500
IHC: 1:200
ICC: 1:200
- other_names:
- hVDAC1 antibody Outer mitochondrial membrane protein porin 1 antibody Plasmalemmal porin antibody Porin 31HL antibody Porin 31HM antibody Porin antibody VDAC 1 antibody VDAC antibody VDAC-1 antibody Vdac1 antib
- Purification:
- Immunogen affinity purified
- Applications:
- WB, ICC, IHC
- Background:
- Voltage-dependent anion-selective channel (VDAC1) (also referred to as porin, isoform 1) is a small protein, originally discovered in the outer membrane of mitochondria where it constitutes the major pore-forming protein. The porin protein VDAC1 allows to the outer-most membrane of the mitochondrion free permeability to low molecular-weight solutes. VDAC1 has been shown to co-immunoprecipitate with the anti-apoptotic protein Bcl-2 and suggested to be involved in forming the mitochondrial pore which releases cytochrome c during apoptosis.
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