Product Datasheet  
UTF1 Antibody  
Catalog Number: 48148  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q5T230
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • peptide
  • reactivity:  
  • Hu,Ms,Rt
  • appl_detail:  
  • WB: 1:1,000-1:2,000
    IHC: 1:200


  • other_names:  
  • hUTF 1 antibody
    hUTF1 antibody
    Undifferentiated embryonic cell transcription factor 1 antibody
    UTF 1 antibody
    UTF1 antibody
    UTF1_HUMAN antibody
  • Purification:  
  • Immunogen affinity purified
  • Specificity:  
  • Applications:  
  • WB, IHC
  • Background:  
  • Undifferentiated embryonic cell transcription factor 1 (UTF1) is expressed in cells of the inner cell mass and the epiblast. Upon activation by Oct-3/4, UTF1 may be responsible for the rapid proliferation and tumorigenic properties of embryonic stem cells. Sox2 is also part of the Oct-3/4-containing complex able to bind the regulatory region of UTF1. UTF1 acts as a transcriptional coactivator of ATF2 and it binds to the N-terminal region of ATF2. Reduced expression in embryonic stem cells (ESCs) is associated with failure to differentiate properly, although self-renewal is unaffected.



 
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