Product Datasheet  
TNF alpha Antibody  
Catalog Number: 48136  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P06804
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • peptide
  • reactivity：  
  • Ms
  • appl_detail：  
  • WB: 1:500-1:1000



  • other_names：  
  • APC1 antibody
    APC1 protein antibody
    Cachectin antibody
    DIF antibody
    Differentiation inducing factor antibody
    Macrophage cytotoxic factor antibody
    Tnf antibody
    TNF superfamily, member 2 antibody
    TNF, macrophage deriv
  • Purification：  
  • Immunogen affinity purified
  • Specificity：  
  • Applications：  
  • WB
  • Background：  
  • TNF-α, the prototypical member of the TNF protein superfamily, is a homotrimeric type-II membrane protein. Membrane bound TNF-α is cleaved by the metalloprotease TACE/ADAM17 to generate a soluble homotrimer. Both membrane and soluble forms of TNF-α are biologically active. TNF-α is produced by a variety of immune cells including T cells, B cells, NK cells and macrophages. TNF-α plays a key regulatory role in infammation and host defense against bacterial infection, notably Mycobacterium tuberculosis.



 
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