Product Datasheet
SOX2 Antibody
Catalog Number: 48128
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P48431
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- appl_detail:
- WB: 1:500-1:1000
ICC: 1:20-1:50
- other_names:
- ANOP3 antibody cb236 antibody Delta EF2a antibody lcc antibody MCOPS3 antibody MGC148683 antibody MGC2413 antibody RGD1565646 antibody Sex determining region Y box 2 antibody SOX 2 antibody Sox2 antibody
- Purification:
- Immunogen affinity purified
- Background:
- SRY (sex determining region Y)-box 2, also known as SOX2, is a transcription factor that is essential to maintain self-renewal of undifferentiated embryonic stem cells. Sox2, Oct-4 and Nanog co-operate in this network, and siRNA knockdown of either Sox2 or Oct-4 results in loss of pluripotency. POU5F1/OCT4, SOX2, MYC/c-Myc and KLF4 are the four Yamanaka factors. When combined, these factors are sufficient to reprogram differentiated cells to an embryonic-like state designated iPS (induced pluripotent stem) cells
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