Product Datasheet  
alpha 1-antitrypsin Antibody  
Catalog Number: 48127  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P01009
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • peptide
  • reactivity：  
  • Hu
  • appl_detail：  
  • WB: 1:1,000



  • other_names：  
  • A1A antibody
    A1AT antibody
    A1AT_HUMAN antibody
    AAT antibody
    Alpha 1 antiproteinase antibody
    Alpha 1 antitrypsin antibody
    Alpha 1 antitrypsin null antibody
    Alpha 1 protease inhibitor antibody
    Alpha-1 protease inhibit
  • Purification：  
  • Immunogen affinity purified
  • Specificity：  
  • Applications：  
  • WB
  • Background：  
  • Alpha 1-Antitrypsin is a inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. It Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. Defects in SERPINA1 are the cause of alpha-1-antitrypsin deficiency (A1ATD). A disorder whose most common manifestation is emphysema, which becomes evident by the third to fourth decade. A less common manifestation of the deficiency is liver disease, which occurs in children and adults, and may result in cirrhosis and liver failure.



 
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