Product Datasheet
IL1RL1 Antibody
Catalog Number: 48024
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P14719
- Form of Antibody:
- 1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- reactivity:
- Hu, Ms, zebrafish
- other_names:
- DER-4 antibody DER4 antibody FIT 1 antibody Growth stimulation expressed antibody homolog of mouse growth stimulation-expressed antibody Il1rl1 antibody IL33R antibody ILRL1_HUMAN antibody Interleukin 1 receptor lik
- Purification:
- Immunogen affinity purified
- Applications:
- WB, ICC, IHC, FC
- Background:
- ST2 known as IL1RL1a membrane proteinbelongs to the interleukin-1 receptor family with three Ig-like C2-type (immunoglobulin-like) domains and a TIR domain. Predominantly ST2 expressed in hematopoietic tissues, and in macrophage,erythroid, epithelial and fibroblast cell lines. ST2 is a receptor for interleukin-33 (IL-33) which upon stimulation recruits the signaling molecules MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8.
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