Product Datasheet
Vitamin K-dependent protein S Antibody
Catalog Number: 48020
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P07225
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- other_names:
- Preproprotein S antibody Propiece of latent protein S antibody PROS 1 antibody PROS antibody PROS_HUMAN antibody proS1 antibody Protein S alpha antibody Protein Sa antibody PS 21 antibody PS 22 antibody PS
- Purification:
- Immunogen affinity purified
- Background:
- Protein S is a vitamin K-dependent plasma glycoprotein synthesized in the endothelium. In the circulation, Protein S exists in two forms: a free form and a complex form bound to complement protein C4b. In the plasma, circulating Protein S becomes inactive upon complexing with C4b-binding protein (C4BP); 60-70% of Protein S circulates in complex with C4BP. Its major function is as a cofactor to facilitate the action of activated protein C (APC) on its substrates, activated factor V (FVa), and activated factor VIII (FVIIIa).
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