Product Datasheet
Carcino Embryonic Antigen CEA Antibody
Catalog Number: 48010
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P06731
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 25% Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Synthetic peptide corresponding to a region of human Carcino Embryonic Antigen CEA.
- appl_detail:
- WB: 1:1,000-1:2,000
IHC:1:50-1:200
ICC:1:50-1:200
FC:1:50-1:100
- other_names:
- Carcinoembryonic antigen antibody
Carcinoembryonic antigen-related cell adhesion molecule 5 antibody
CD66e antibody
CEA antibody
Ceacam5 antibody
CEAM5_HUMAN antibody
DKFZp781M2392 antibody
Meconium antigen
- Purification:
- Peptide affinity purified
- Applications:
- WB, ICC, IHC, FC
- Background:
- The CD66 (carcinoembryonic antigen, CEA, biliary glycoprotein I, BGP-1, CEACAM) immunoglobulin superfamily of genes encode cell adhesion proteins, which are expressed at higher levels in tumorous tissues than in normal tissues. The human CD66 gene family is a diverse set of glycoproteins of epithelial and hematopoietic lineage that comprises 29 genes, which map to chromosome position 19q13.1-q13.2. CD66A, CD66B, CD66C, CD66D, CD66E and CD66F are the best characterized CD66 antigens, and CD66A-D expression upregulates on the surface of granulocytes upon stimulation. Certain CD66 family members mediate homotypic and heterotypic intercellular adhesion events. CD66E, also known as CEA, is a well known tumor marker and a heavily glycosylated GPI-linked cell surface molecule.
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